Gene regulation studies

  1. Borovok, Ilya, Hamutal Kahel-Raifer, Sadanari Jindou Liat Bahari, Yakir Nataf, Yuval Shoham, Edward Bayer, Raphael Lamed. Unique set of putative membrane-associated anti-sigma factors in Clostridium thermocellum suggests a novel extracellular carbohydrate-sensing mechanism involved in gene regulation. FEMS Microbiol. Lett. 308:84–93, 2010.
  2. Gat O., A. Lapidot, I. Alchanati, C. Regueros and Y. Shoham. Cloning and DNA sequence of the gene coding for Bacillus stearothermophilus T-6 xylanase. Appl. Enviorn. Microbiol. 60:1889-1896, 1994.
  3. Kaustov, L., Kababya, S., Du, S., Baasov, T., Gropper, S., Shoham, Y., and Schmidt, A. Structural and mechanistic investigation of 3-deoxy-D-manno-octulosonate-8-phosphate syntahase by solid-state REDOR NMR. Biochemistry 39:14865-14876, 2000.
  4. Orly Tabachnikov and Yuval Shoham. Functional Characterization of the Galactan Utilization System of Geobacillus stearothermophilus. FEBS J 280:950-964, 2013.
  5. Shulami, S., O. Gat, A.L. Sonenshein, and Y. Shoham. The glucuronic acid utilization gene cluster from Bacillus stearothermophilus T-6. J. Bacteriol. 181:3695-3704, 1999
  6. Smadar Shulami, Ayelet Raz-Pasteur, Orly Tabachnikov, Sarah Gilead-Gropper, Itzhak Shner, and Yuval Shoham. The L-arabinan utilization system of Geobacillus stearothermophilus J. Bacteriol. 193:2838-2850, 2011.
  7. Smadar Shulami, Galia Zaide, Gennady Zolotnitsky, Yael Langut, Geoff Feld, Abraham L. Sonenshein and Yuval Shoham. A two-component system regulates the expression of an ABC transporter for xylo-oligosaccharides in Geobacillus stearothermophilus. Appl. Enviorn. Microbiol. 73:874-884, 2007.
  8. Smadar Shulami, Ofer Shenker, Yael Langut, Noa Lavid, Orit Gat, Galia Zaide, Arik Zehavi, Abraham L. Sonenshein, and Yuval Shoham. Multiple regulatory mechanisms control the expression of the Geobacillus stearothermophilus gene for extracellular xylanase. J. Biol. Chem (in press)
  9. Tali W. Dror, Adi Rolider, Edward A. Bayer, Raphael Lamed and Yuval Shoham. Regulation of major cellulosomal endoglucanases of Clostridium thermocellum differs from that of a prominent cellulosomal xylanase. J. Bacteriol. 187:2261-2266, 2005.
  10. Tali W. Dror, Adi Rolider, Edward A. Bayer, Raphael Lamed and Yuval Shoham. Regulation of expression of scaffoldin-related genes in Clostridium thermocellum. J. Bacteriol. 185:5109-5116, 2003.
  11. Tali W. Dror, Ely Morag, Adi Rolider, Edward A. Bayer, Raphael Lamed and Yuval Shoham. Regulation of the cellulosomal celS (cel48A) gene of Clostridium thermocellum is growth-rate dependent. J. Bacteriol. 185:2042-3048, 2003.
  12. Yakir Nataf, Liat Bahari, Hamutal Kahel-Raifer, Ilya Borovok, Raphael Lamed, Edward A. Bayer, Abraham L. Sonenshein and Yuval Shoham. Clostridium thermocellum cellulosomal genes are regulated by extracytoplasmic polysaccharides via alternative sigma factors. Proc. Natl. Acad. Sci. USA 107:18646–18651, 2010.
  13. Yakir Nataf, Sima Yaron, Frank Stahl, Raphael Lamed, Edward A. Bayer, Thomas-Helmut Scheper, Abraham L. Sonenshein, and Yuval Shoham. Cellodextrin and laminaribiose ABC transporters in Clostridium thermocellum. J. Bacteriol. 191:203-209,2009.
  14. Andy Sand, Evert K. Holwerda, Natalie M. Ruppertsberger, Marybeth Maloney, Daniel G. Olson, Yakir Nataf, Ilya Borovok, Abraham L. Sonenshein, Edward A. Bayer, Raphael Lamed, Lee R. Lynd and Yuval Shoham.  Three cellulosomal xylanase genes in Clostridium thermocellum are regulated by both vegetative SigA (sigma A) and alternative SigI6 (sigma I6) factors.  FEBS Letters 589: 3133–3140, 2015.