3D structure of an extra-cellular xylanase
Our research is in the field of applied enzymology and molecular and industrial microbiology. Many of our studies involve thermophilic microorganisms and thermostable enzymes for biotechnological applications. Special emphasize is on the hemicellulolytic and cellulolytic systems in the thermophilic bacteria Geobacillus stearothermophilus and Clostridium thermocellum. Our research is highly multidisciplinary, combining fermentation technology, physiology, gene regulation at the molecular level, protein engineering, directed evolution, structure-function analysis and metagenomics.